I have done this swap myself on an E-350. You need to get the brackets that attach to the upper radiator support, you also need the upper radiator support that the hood latch bolts to, otherwise you will be drilling holes, and making spacers all day if you try to reuse your original. You have to swap out the hood latch cable because the old one will not attach to the newer style hood latch. You will have to make spacers if you wish to put more than two bolts in the upper fender, the inner fender apron on your truck has a flat surface to bolt the fenders onto versus the newer style vans which have a raised section on the fender aprons to accomodate the shape of the newer fenders.
Here are a couple pics, the first one shows the upper radiator support which you will need as well as the two brackets you need to properly space the reinforcement panel which holds your headlights, i circled them in red. The other picture is a new style inner fender apron laying down. The red line i made indicates the shape of the surface the fender bolts to versus the flat surface on your existing aprons. As a side note.. the transmission cooler brackets are also different. Nothing major, just enough to make it a nuisance swap if you dont have all of the proper parts.
Once the swap is complete you have enough room behind the grille for the wife and kids to ride. Hope this helps....