My tires stick out almost exactly as marret's do. Shadetree brings up a good point, you need to keep in mind that the rear tire can interfere with the door if you have a slider. I do and mine does rub a bit. I shimmed up my slider track ever so slightly and can get my door open just fine now.
2015 Chevy Express 3500 Duramax
w/ Quigley 4x4 & Agile Fox shocks
Sold 2005 E350 Chateau
Quigley with Agile RIP, 6.0 PSD