Stick shift and 4x4 aside, this is a $1,500 van. At best.
You could buy any other van, have Agile throw a TTB underneath, and pay somebody else to do the trans swap, and be miles ahead in cost saving, reliability, and driveabilty.
FWIW - Most of the manual trans parts are available in the E-series parts catalogue, because Ford sold the stripped-chassis with that option through '01 or so. The only real custom parts seem to be the pedal and shifter.
2000 E450 dually V10 wagon