Just check the extra height required for the 'charger. I suspect it will fit. The superchargers I've seen all took up extra space in the valley, and were not taller.
You might have to switch to hyrdoboost brakes, if you need more space for the drive belt.
Whipple used to make a V10 supercharger, and some of those went into vans. They don't make that model anymore though.
Superchargers are parasitic though, so they generally reduce efficiency.
If you also want better efficiency, you may want to go with a turbo instead. STS sells a bolt-on F150 kit. Should work fine on the vans too. Most F150 5.4L exhausts also work on the vans.