315 tires, 3.54 and relatively stock 7.3is going to be very disappointing.
We have 285(32.7), 3.73 and Hydra chipped 7.3. The original gearing was 3.54(3.55 actually). Changed to the 3.73's and it has been okay but there are times I feel 4.10 would better.
The 7.3 really likes to turn around 1,800 to 2,000 rpm at cruising speed. For our combination that is around 68 to 74 mph which is a tad higher than what feels comfortable. Often, I am at 63 mph which aerodynamically and fuel mileage is manageable. That puts rpm's closer to 1,720 and below where the 7.3 is happiest. Exhaust Gas Temp management and downshifting is needed on hills since I am dropping below the power band rpms.
https://purperformance.com/p-29669-rpm-calculator.html great calculator for tire size /gear ratio's/speed. The 4r100 has a top gear ratio of .71 in overdrive.
For Vincent, he needs to decide the balance of what speed on the highways he wants vs fuel economy vs towing. Using the calculator for his specs and running around 100kmh would indicate 4.30 would be a nice gear ratio. Driving at 120kmh would point to 4.1.
It is the hills that will be the place that the 4.3 will have 7.3 spinning nicely at around 2,000 rpm / OD Off / 80kmh