Don't listen to your inner self which tells you not to cut up a good vehicle body.
Do get out the sawzall and fire away. It's a 20 year old van at least (guessing average for most of us) and there is no way you're going to get the clearance you want otherwise. Plus, are you going to ever be happy with the van without the tires you want on it? Are you expecting this will impact resale? I suspect no on these two questions.
There are two ways to accomplish it without cutting , both more expensive, time consuming and difficult. First is to move the front axle forward, second is to get those crafty fiberglass pre-runner looking front quarters that someone here made awhile back. I can't remember who did it.
I recently trimmed mine on my 2011 for 35"s. Basically remove the Bushwacker, if you have it, remove the inner liner or take screws out of rear and fold it up out of the way with the help of some bungees or whatever, and then figure out how much you need to trim. I trimmed back a triangle about an inch wide but maybe 2-3 inches long on mine and then gently hammered/bent/folded the metal until I was happy. Then painted my mess to ward off rust and reapplied Bushwacker. I did have to manipulate the fender flare and add a couple of screws to get it back where I wanted it. Sadly I have no pics.
After I did this, of course, I was talking to MG (Metalworks) and he reminded me that I could've used a heat gun to very easily reshape the Bushwacker. I might still do that one day when I run out of other projects but I have no rub.