I have a 01 V10 and haven't lost a wink of sleep.
And if you search online, yes there are cases of people blowing a plug or two. However, you need to realize that for every 1 person w/ an issue, there are a 100 people w/ absolutely no issues. It's the way the online world works.
And if you search there are also things you can do such as periodically making sure he plugs are tightened to the proper torque and god-forbid if something actually happens to you, check out some of the reviews of the insert repairs, not the basic helicoil kit.
Personally if the van is in tip top shape - go for it!
2002 EB51 7.3L w/ Stage 2- UJoint 6" 4x4 Conversion
2001 RB50 V10 Quigley- SOLD